英文标点符号与中文标点符号的使用有所不同，能掌握并正确使用英文标点符号也是英文写作的基本要求。
直接疑问句
直接疑问句末尾用问号，间接疑问句末尾用句号。
直接疑问句：What is she doing tonight?
间接疑问句：I wonder what she’s doing tonight.
直接疑问句：The question is, Does anyone support this legislation?
间接疑问句：The question was whether anyone supported the legislation.
句中的直接疑问句
直接疑问句出现在长句中，一般以句号结尾。注意下面例子，句法上要求使用逗号的位置以问号替换了逗号。
Would they make it on time? she wondered.
The key question, Can the two sides reach a compromise? was not answered.
“What are we having for dinner?” his son asked.
著作标题含有问号的情况
与上述例子不同，若问号是著作标题的一部分，则按句法要求保留逗号。
Have you read Do Androids Dream of Electric Sheep?, the Philip Dick novel that inspired the movie Blade Runner?
“Is He Living or Is He Dead?,” by Mark Twain, is one of my favorite stories.
带有问号的标题出现在句末，且句子本身应以问号或句号结束时，省略应加的问号或句号。
Have you read Do Androids Dream of Electric Sheep?
I have not read Mark Twain’s “Is He Living or Is He Dead?”
请求
以疑问形式表达的请求要以句号结尾。
Would you please send this report to the person indicated on the cover.
用于表达不确定
编辑时可使用问号表示不确定，标注在圆括号或方括号中。一些专家会在不确定的词和左括号之间留出一个空格，另一些专家则省略此等空格，用例如下：
The patient reported taking 15(?) milligrams of alprazolam.
According to his biographer, Smith “bought the company in 1985 [1984?], but wasn’t actively engaged in its management until 1990.”
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